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Aprea Therapeutics, Inc. (APRE)
Price & fundamentals
Compound Annual Growth Rate(CAGR)
Historical valuation multiples
Ratio observations in the selected window
| Price date | EPS fiscal end | Basic P/E (×) | Diluted P/E (×) | P/S (×) | P/FCF (×) |
|---|
Profit margins
Calculation inputs, filings & unavailable observations
Yield, cash conversion & capital returns
Calculation inputs, filings & unavailable observations
Price & growth-based reference
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YEAR-OVER-YEAR
Annual metric change
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Annual data and sources
Aprea Therapeutics, Inc. (APRE) · Nasdaq · USD · Sector unavailable · CIK 0001781983
Annual coverage: 2017-12-31–2025-12-31 (9 periods). Financial snapshot built 2026-10-09.
APRE annual financial history
All stored annual observations, independent of the chart window. Per-share amounts in USD. Unavailable values are not zero.
See the calculation and limitations.
| Fiscal year / end | Basic EPS | Diluted EPS | FCF / share | Dividends / share | Fiscal-year dividend yield | Filing sources |
|---|---|---|---|---|---|---|
| 2025 2025-12-31 | -1.93 | -1.93 | Unavailable | Unavailable | Unavailable | Basic EPS (2026-03-16) Diluted EPS (2026-03-16) |
| 2024 2024-12-31 | -2.35 | -2.35 | -2.46 | Unavailable | Unavailable | Basic EPS (2026-03-16) Diluted EPS (2026-03-16) Operating cash flow (2026-03-16) · Capex (2026-03-16) |
| 2023 2023-12-31 | -3.95 | -3.95 | -3.39 | Unavailable | Unavailable | Basic EPS (2025-03-25) Diluted EPS (2025-03-25) Operating cash flow (2025-03-25) · Capex (2025-03-25) |
| 2022 2022-12-31 | -67.99 | -67.99 | Unavailable | Unavailable | Unavailable | Basic EPS (2024-03-26) Diluted EPS (2024-03-26) |
| 2021 2021-12-31 | -34.88 | -34.88 | Unavailable | Unavailable | Unavailable | Basic EPS (2024-03-26) Diluted EPS (2024-03-26) |
| 2020 2020-12-31 | -50.61 | -50.61 | -39.58 | Unavailable | Unavailable | Basic EPS (2023-03-30) Diluted EPS (2023-03-30) Operating cash flow (2023-03-30) · Capex (2023-03-30) |
| 2019 2019-12-31 | -93.40 | -93.40 | -89.10 | Unavailable | Unavailable | Basic EPS (2022-03-15) Diluted EPS (2022-03-15) Operating cash flow (2022-03-15) · Capex (2022-03-15) |
| 2018 2018-12-31 | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Operating cash flow (2021-03-16) · Capex (2021-03-16) |
| 2017 2017-12-31 | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Source unavailable |
Annual per-share context (USD/share)
Complete annual history, independent of chart loading and range. Revenue/share is annual revenue per average diluted share. Debt/share is borrowings per year-end common share, excluding leases. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | Revenue / share | Total debt / share | Inputs & filing sources |
|---|---|---|---|
| 2025-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 6538722; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 8192538 averageDilutedShares (2026-03-16)periodEndShares (2026-03-16) |
| 2024-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 5509921; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 5481055 averageDilutedShares (2026-03-16)periodEndShares (2026-03-16) |
| 2023-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 3617607; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 3736673 averageDilutedShares (2025-03-25)periodEndShares (2025-03-25) |
| 2022-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 1657055; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 2655269 averageDilutedShares (2024-03-26)periodEndShares (2024-03-26) |
| 2021-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 1064325; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 1092967 averageDilutedShares (2024-03-26)periodEndShares (2023-03-30) |
| 2020-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 1056681; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 1059341.35 averageDilutedShares (2023-03-30)periodEndShares (2022-03-15) |
| 2019-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: 300124.3; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 1051137.6 averageDilutedShares (2022-03-15)periodEndShares (2021-03-16) |
| 2018-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 57768.3 periodEndShares (2020-03-27) |
| 2017-12-31 | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: No positive common shares on the exact fiscal-end date Source unavailable |
Annual returns and cash generation (%)
Complete annual history, independent of chart loading and range. FCF margin and FCF / net income use matching annual totals. ROCE uses positive exact opening and closing capital-employed bases. Inputs, scopes and unavailable reasons are disclosed below. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | FCF margin (%) | FCF / net income (%) | ROCE (%) | Inputs & filing sources |
|---|---|---|---|---|
| 2025-12-31 | Unavailable | Unavailable | -78.34 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-12599569,"tag":"ProfitLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"operatingIncome":{"value":-13233836,"tag":"OperatingIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingAssets":{"value":23979493,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingCurrentLiabilities":{"value":3360975,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingCapitalEmployed":{"value":20618518,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":19307455,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":22849885,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":15933401,"tag":"Assets","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingCurrentLiabilities":{"value":2764358,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingCapitalEmployed":{"value":13169043,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":12441682,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCash":{"value":14599347,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2025-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-12599569,"tag":"NetIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":16893780.5,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -78.3355507667452 cashConversion component 1 (2026-03-16)roce component 1 (2026-03-16) · roce component 2 (2026-03-16) · roce component 3 (2026-03-16) · roce component 4 (2026-03-16) · roce component 5 (2026-03-16) |
| 2024-12-31 | Unavailable | Unavailable | -73.65 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-13572196,"capex":{"accession":"0001104659-26-028068","end":"2024-12-31","filed":"2026-03-16","form":"10-K","start":"2024-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001104659-26-028068","end":"2024-12-31","filed":"2026-03-16","form":"10-K","start":"2024-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-12958711,"tag":"ProfitLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"operatingIncome":{"value":-14319655,"tag":"OperatingIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingAssets":{"value":22650174,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-25","accession":"0001558370-25-003588","form":"10-K"},"openingCurrentLiabilities":{"value":4385605,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-25","accession":"0001558370-25-003588","form":"10-K"},"openingCapitalEmployed":{"value":18264569,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":16953506,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":21606820,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-25","accession":"0001558370-25-003588","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":23979493,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingCurrentLiabilities":{"value":3360975,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingCapitalEmployed":{"value":20618518,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":19307455,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCash":{"value":22849885,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-12958711,"tag":"NetIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-16","accession":"0001104659-26-028068","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":19441543.5,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -73.65492868403169 fcfMargin component 1 (2026-03-16) · fcfMargin component 2 (2026-03-16)cashConversion component 1 (2026-03-16) · cashConversion component 2 (2026-03-16) · cashConversion component 3 (2026-03-16) roce component 1 (2026-03-16) · roce component 2 (2025-03-25) · roce component 3 (2025-03-25) · roce component 4 (2026-03-16) · roce component 5 (2026-03-16) |
| 2023-12-31 | Unavailable | Unavailable | -68.43 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-12270701,"capex":{"accession":"0001558370-25-003588","end":"2023-12-31","filed":"2025-03-25","form":"10-K","start":"2023-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001558370-25-003588","end":"2023-12-31","filed":"2025-03-25","form":"10-K","start":"2023-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-14286756,"tag":"ProfitLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-25","accession":"0001558370-25-003588","form":"10-K"},"operatingIncome":{"value":-15471963,"tag":"OperatingIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-25","accession":"0001558370-25-003588","form":"10-K"},"openingAssets":{"value":30155827,"tag":"Assets","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-03-26","accession":"0001558370-24-003886","form":"10-K"},"openingCurrentLiabilities":{"value":3201086,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-03-26","accession":"0001558370-24-003886","form":"10-K"},"openingCapitalEmployed":{"value":26954741,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":25643678,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-03-25","accession":"0001558370-25-003588","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":3201086,"tag":"Liabilities","unit":"USD","start":null,"end":"2022-12-31","filed":"2023-03-30","accession":"0001558370-23-005126","form":"10-K"},"openingCash":{"value":28786647,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-03-26","accession":"0001558370-24-003886","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -68.43077879781889 fcfMargin component 1 (2025-03-25) · fcfMargin component 2 (2025-03-25)cashConversion component 1 (2025-03-25) · cashConversion component 2 (2025-03-25) · cashConversion component 3 (2025-03-25) roce component 1 (2025-03-25) · roce component 2 (2024-03-26) · roce component 3 (2024-03-26) · roce component 4 (2025-03-25) · roce component 5 (2025-03-25) |
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| 2019-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-26739608,"capex":{"accession":"0001558370-22-003671","end":"2019-12-31","filed":"2022-03-15","form":"10-K","start":"2019-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001558370-22-003671","end":"2019-12-31","filed":"2022-03-15","form":"10-K","start":"2019-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-28059807,"tag":"ProfitLoss","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-15","accession":"0001558370-22-003671","form":"10-K"},"operatingIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingAssets":{"value":66022638,"tag":"Assets","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"openingCurrentLiabilities":{"value":4868109,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"openingCapitalEmployed":{"value":61154529,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":-51436102,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2018-12-31","filed":"2022-03-15","accession":"0001558370-22-003671","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":4868109,"tag":"Liabilities","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"openingCash":{"value":65675931,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2019-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-28059807,"tag":"NetIncomeLoss","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-15","accession":"0001558370-22-003671","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-15","accession":"0001558370-22-003671","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":92850340,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: operatingIncome; Missing or conflicting matching SEC fact fcfMargin component 1 (2022-03-15) · fcfMargin component 2 (2022-03-15)cashConversion component 1 (2022-03-15) · cashConversion component 2 (2022-03-15) · cashConversion component 3 (2022-03-15) roce component 1 (2020-03-27) · roce component 2 (2020-03-27) · roce component 3 (2021-03-16) · roce component 4 (2021-03-16) |
| 2018-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-15253936,"capex":{"accession":"0001558370-21-003083","end":"2018-12-31","filed":"2021-03-16","form":"10-K","start":"2018-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001558370-21-003083","end":"2018-12-31","filed":"2021-03-16","form":"10-K","start":"2018-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-15528269,"tag":"ProfitLoss","unit":"USD","start":"2018-01-01","end":"2018-12-31","filed":"2021-03-16","accession":"0001558370-21-003083","form":"10-K"},"operatingIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2017-12-31"},"openingParentEquity":{"value":-35765195,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2017-12-31","filed":"2021-03-16","accession":"0001558370-21-003083","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2017-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":66022638,"tag":"Assets","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"closingCurrentLiabilities":{"value":4868109,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"closingCapitalEmployed":{"value":61154529,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":-51436102,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2018-12-31","filed":"2022-03-15","accession":"0001558370-22-003671","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":4868109,"tag":"Liabilities","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"closingCash":{"value":65675931,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2018-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2018-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-15528269,"tag":"NetIncomeLoss","unit":"USD","start":"2018-01-01","end":"2018-12-31","filed":"2021-03-16","accession":"0001558370-21-003083","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2018-01-01","end":"2018-12-31","filed":"2021-03-16","accession":"0001558370-21-003083","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: operatingIncome, openingCapitalEmployed; Missing or conflicting matching SEC fact; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2017-12-31 fcfMargin component 1 (2021-03-16) · fcfMargin component 2 (2021-03-16)cashConversion component 1 (2021-03-16) · cashConversion component 2 (2021-03-16) · cashConversion component 3 (2021-03-16) roce component 1 (2020-03-27) · roce component 2 (2020-03-27) |
| 2017-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-15190250,"tag":"ProfitLoss","unit":"USD","start":"2017-01-01","end":"2017-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"operatingIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2016-12-31"},"openingParentEquity":{"value":-21465545,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2016-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2016-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCapitalEmployed":{"value":null,"inputNames":["closingAssets","closingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2017-12-31"},"closingParentEquity":{"value":-35765195,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2017-12-31","filed":"2021-03-16","accession":"0001558370-21-003083","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2017-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-15190250,"tag":"NetIncomeLoss","unit":"USD","start":"2017-01-01","end":"2017-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2017-01-01","end":"2017-12-31","filed":"2020-03-27","accession":"0001558370-20-003257","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: operatingIncome, openingCapitalEmployed, closingCapitalEmployed; Missing or conflicting matching SEC fact; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2016-12-31; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2017-12-31 cashConversion component 1 (2020-03-27) |
Annual operating facts
Complete annual history, independent of chart loading and range. Operating margin is operating profit as a percentage of revenue; net margin is consolidated net profit as a percentage of revenue. Negative margins show losses. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | Revenue (USD) | Operating margin (%) | Net margin (%) | Inputs & filing sources |
|---|---|---|---|---|
| 2025-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: -13233836; netIncome: -12599569 operatingIncome (2026-03-16)netIncome (2026-03-16) |
| 2024-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: -14319655; netIncome: -12958711 operatingIncome (2026-03-16)netIncome (2026-03-16) |
| 2023-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: -15471963; netIncome: -14286756 operatingIncome (2025-03-25)netIncome (2025-03-25) |
| 2022-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: -113392228; netIncome: -112662027 operatingIncome (2024-03-26)netIncome (2024-03-26) |
| 2021-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: -37446353; netIncome: -37127303 operatingIncome (2024-03-26)netIncome (2024-03-26) |
| 2020-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: No unambiguous matching annual USD fact; netIncome: -53478812 netIncome (2023-03-30) |
| 2019-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: No unambiguous matching annual USD fact; netIncome: -28059807 netIncome (2022-03-15) |
| 2018-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: No unambiguous matching annual USD fact; netIncome: -15528269 netIncome (2021-03-16) |
| 2017-12-31 | Unavailable | Unavailable | Unavailable | Inputs & filingsrevenue: No unambiguous matching annual USD fact; operatingIncome: No unambiguous matching annual USD fact; netIncome: -15190250 netIncome (2020-03-27) |
Aprea Therapeutics, Inc. (APRE) P/E ratio history
The interactive P/E chart contains all 367 stored weekly price points (2019-10-04–2026-10-08); 0 have an eligible basic or diluted ratio. Annual EPS is carried forward from its fiscal end. Use the P/E range bar or any other chart range bar to change all five chart windows.
Fiscal-year-end snapshots
No positive annual EPS with an eligible fiscal-year-end price is available in this snapshot.
Annual P/E = eligible fiscal-year-end close ÷ reported annual EPS. This is retrospective annual P/E, not TTM or forward P/E. Why we use annual data. Missing or non-positive EPS and missing eligible prices produce unavailable ratios.
Explore the P/E chart and optional reference lines · How P/E history is calculated.
Complete annual P/E history (9 fiscal periods)
| Fiscal end | Price date | Close | Price basis | Basic P/E | Diluted P/E | EPS filings |
|---|---|---|---|---|---|---|
| 2025-12-31 | 2025-12-26 | 0.98 | Adjusted close | Unavailable | Unavailable | Basic EPS (2026-03-16) Diluted EPS (2026-03-16) |
| 2024-12-31 | 2024-12-27 | 3.37 | Adjusted close | Unavailable | Unavailable | Basic EPS (2026-03-16) Diluted EPS (2026-03-16) |
| 2023-12-31 | 2023-12-29 | 4.70 | Adjusted close | Unavailable | Unavailable | Basic EPS (2025-03-25) Diluted EPS (2025-03-25) |
| 2022-12-31 | 2022-12-30 | 6.62 | Adjusted close | Unavailable | Unavailable | Basic EPS (2024-03-26) Diluted EPS (2024-03-26) |
| 2021-12-31 | 2021-12-31 | 57.40 | Adjusted close | Unavailable | Unavailable | Basic EPS (2024-03-26) Diluted EPS (2024-03-26) |
| 2020-12-31 | 2020-12-31 | 98.40 | Adjusted close | Unavailable | Unavailable | Basic EPS (2023-03-30) Diluted EPS (2023-03-30) |
| 2019-12-31 | 2019-12-27 | 990.60 | Adjusted close | Unavailable | Unavailable | Basic EPS (2022-03-15) Diluted EPS (2022-03-15) |
| 2018-12-31 | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Source unavailable |
| 2017-12-31 | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Source unavailable |
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