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Definium Therapeutics, Inc. (DFTX)

Historical prices through 2026-10-08Latest fiscal period 2025-12-31

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Definium Therapeutics, Inc. (DFTX) · Nasdaq · USD · Sector unavailable · CIK 0001813814

Annual coverage: 2020-12-31–2025-12-31 (6 periods). Financial snapshot built 2026-10-09.

DFTX annual financial history

All stored annual observations, independent of the chart window. Per-share amounts in USD. Unavailable values are not zero.

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Annual EPS, cash flow, dividends, and fiscal-year dividend yield for Definium Therapeutics, Inc.
Fiscal year / end	Basic EPS	Diluted EPS	FCF / share	Dividends / share	Fiscal-year dividend yield	Filing sources
2025 2025-12-31	-2.06	-2.06	Unavailable	Unavailable	Unavailable	Basic EPS (2026-02-26) Diluted EPS (2026-02-26)
2024 2024-12-31	-1.54	-1.54	Unavailable	Unavailable	Unavailable	Basic EPS (2026-02-26) Diluted EPS (2026-02-26)
2023 2023-12-31	-2.44	-2.44	Unavailable	Unavailable	Unavailable	Basic EPS (2025-03-06) Diluted EPS (2025-03-06)
2022 2022-12-31	-1.84	-1.84	Unavailable	Unavailable	Unavailable	Basic EPS (2024-02-28) Diluted EPS (2024-02-28)
2021 2021-12-31	-3.40	-3.40	Unavailable	Unavailable	Unavailable	Basic EPS (2023-03-09) Diluted EPS (2023-03-09)
2020 2020-12-31	Unavailable	Unavailable	Unavailable	Unavailable	Unavailable	Source unavailable

Annual per-share context (USD/share)

Complete annual history, independent of chart loading and range. Revenue/share is annual revenue per average diluted share. Debt/share is borrowings per year-end common share, excluding leases. Missing inputs remain unavailable. Metric definitions.

Fiscal end	Revenue / share	Total debt / share	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 89327608; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 98776265 averageDilutedShares (2026-02-26) periodEndShares (2026-02-26)
2024-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 70461067; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 75100763 averageDilutedShares (2026-02-26) periodEndShares (2026-02-26)
2023-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 39157420; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 41101303 averageDilutedShares (2025-03-06) periodEndShares (2025-03-06)
2022-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 30857463; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 37979136 averageDilutedShares (2024-02-28) periodEndShares (2024-02-28)
2021-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 27377082; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 28126414 averageDilutedShares (2023-03-09) periodEndShares (2023-03-09)
2020-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: No positive common shares on the exact fiscal-end date Source unavailable

Annual returns and cash generation (%)

Complete annual history, independent of chart loading and range. FCF margin and FCF / net income use matching annual totals. ROCE uses positive exact opening and closing capital-employed bases. Inputs, scopes and unavailable reasons are disclosed below. Missing inputs remain unavailable. Metric definitions.

Fiscal end	FCF margin (%)	FCF / net income (%)	ROCE (%)	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	-52.24	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-183793000,"tag":"ProfitLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"operatingIncome":{"value":-166309000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingAssets":{"value":302151000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingCurrentLiabilities":{"value":38849000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingCapitalEmployed":{"value":263302000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":241448000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingTotalEquity":{"value":241448000,"inputNames":["openingParentEquity","openingAssets","openingLiabilities"]},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":60703000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingCash":{"value":273741000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -52.24060159823088 cashConversion component 1 (2026-02-26) roce component 1 (2026-02-26) · roce component 2 (2026-02-26) · roce component 3 (2026-02-26) · roce component 4 (2026-02-26) · roce component 5 (2026-02-26)
2024-12-31	Unavailable	Unavailable	-58.45	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-108679000,"tag":"ProfitLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"operatingIncome":{"value":-103916000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingAssets":{"value":124541000,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"openingCurrentLiabilities":{"value":32246000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"openingCapitalEmployed":{"value":92295000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":78134000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":46407000,"tag":"Liabilities","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"openingCash":{"value":99704000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":302151000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"closingCurrentLiabilities":{"value":38849000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"closingCapitalEmployed":{"value":263302000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":241448000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"closingTotalEquity":{"value":241448000,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":60703000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"closingCash":{"value":273741000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":-108679000,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":-108679000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-02-26","accession":"0001193125-26-076742","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":177798500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -58.44593739542234 cashConversion component 1 (2026-02-26) roce component 1 (2026-02-26) · roce component 2 (2025-03-06) · roce component 3 (2025-03-06) · roce component 4 (2026-02-26) · roce component 5 (2026-02-26)
2023-12-31	Unavailable	Unavailable	-76.81	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-95732000,"tag":"ProfitLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"operatingIncome":{"value":-93866000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"openingAssets":{"value":169993000,"tag":"Assets","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"openingCurrentLiabilities":{"value":17892000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"openingCapitalEmployed":{"value":152101000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":150917000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":19076000,"tag":"Liabilities","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"openingCash":{"value":142142000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -76.81467781796756 cashConversion component 1 (2025-03-06) roce component 1 (2025-03-06) · roce component 2 (2024-02-28) · roce component 3 (2024-02-28) · roce component 4 (2025-03-06) · roce component 5 (2025-03-06)
2022-12-31	Unavailable	Unavailable	-43.40	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-56796000,"tag":"ProfitLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"operatingIncome":{"value":-66331000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"openingAssets":{"value":164002000,"tag":"Assets","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"openingCurrentLiabilities":{"value":10408000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"openingCapitalEmployed":{"value":153594000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":151664000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2021-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":12338000,"tag":"Liabilities","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"openingCash":{"value":133539000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2021-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":169993000,"tag":"Assets","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"closingCurrentLiabilities":{"value":17892000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"closingCapitalEmployed":{"value":152101000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":150917000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-03-06","accession":"0000950170-25-034176","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":19076000,"tag":"Liabilities","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"closingCash":{"value":142142000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2022-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-56796000,"tag":"NetIncomeLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":-56796000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":152847500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -43.39684980127251 cashConversion component 1 (2024-02-28) roce component 1 (2024-02-28) · roce component 2 (2023-03-09) · roce component 3 (2023-03-09) · roce component 4 (2024-02-28) · roce component 5 (2024-02-28)
2021-12-31	Unavailable	Unavailable	-80.87	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-93036000,"tag":"ProfitLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"operatingIncome":{"value":-93854000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"openingAssets":{"value":81519000,"tag":"Assets","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"openingCurrentLiabilities":{"value":3008000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"openingCapitalEmployed":{"value":78511000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":75868000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2020-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":5651000,"tag":"Liabilities","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"openingCash":{"value":80094000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2020-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":164002000,"tag":"Assets","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"closingCurrentLiabilities":{"value":10408000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"closingCapitalEmployed":{"value":153594000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":151664000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2021-12-31","filed":"2024-02-28","accession":"0000950170-24-021656","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":12338000,"tag":"Liabilities","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"closingCash":{"value":133539000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2021-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-93036000,"tag":"NetIncomeLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":-1157000,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"pretaxIncome":{"value":-94193000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Positive pretax income required"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Positive pretax income required"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":116052500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -80.87201912927338 cashConversion component 1 (2023-03-09) roce component 1 (2023-03-09) · roce component 2 (2022-03-28) · roce component 3 (2022-03-28) · roce component 4 (2023-03-09) · roce component 5 (2023-03-09)
2020-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-33937000,"tag":"ProfitLoss","unit":"USD","start":"2020-01-01","end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"operatingIncome":{"value":-33030000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2020-01-01","end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2019-12-31"},"openingParentEquity":{"value":4776000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2019-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2019-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":81519000,"tag":"Assets","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"closingCurrentLiabilities":{"value":3008000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"closingCapitalEmployed":{"value":78511000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":75868000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2020-12-31","filed":"2023-03-09","accession":"0000950170-23-007053","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":5651000,"tag":"Liabilities","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"closingCash":{"value":80094000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2020-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-33937000,"tag":"NetIncomeLoss","unit":"USD","start":"2020-01-01","end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":-33937000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2020-01-01","end":"2020-12-31","filed":"2022-03-28","accession":"0000950170-22-004724","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2019-12-31 cashConversion component 1 (2022-03-28) roce component 1 (2022-03-28) · roce component 2 (2022-03-28) · roce component 3 (2022-03-28)

Annual operating facts

Complete annual history, independent of chart loading and range. Operating margin is operating profit as a percentage of revenue; net margin is consolidated net profit as a percentage of revenue. Negative margins show losses. Missing inputs remain unavailable. Metric definitions.

Fiscal end	Revenue (USD)	Operating margin (%)	Net margin (%)	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -166309000; netIncome: -183793000 operatingIncome (2026-02-26) netIncome (2026-02-26)
2024-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -103916000; netIncome: -108679000 operatingIncome (2026-02-26) netIncome (2026-02-26)
2023-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -93866000; netIncome: -95732000 operatingIncome (2025-03-06) netIncome (2025-03-06)
2022-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -66331000; netIncome: -56796000 operatingIncome (2024-02-28) netIncome (2024-02-28)
2021-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -93854000; netIncome: -93036000 operatingIncome (2023-03-09) netIncome (2023-03-09)
2020-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -33030000; netIncome: -33937000 operatingIncome (2022-03-28) netIncome (2022-03-28)

Definium Therapeutics, Inc. (DFTX) P/E ratio history

The interactive P/E chart contains all 285 stored weekly price points (2021-04-30–2026-10-08); 0 have an eligible basic or diluted ratio. Annual EPS is carried forward from its fiscal end. Use the P/E range bar or any other chart range bar to change all five chart windows.

Fiscal-year-end snapshots

No positive annual EPS with an eligible fiscal-year-end price is available in this snapshot.

Annual P/E = eligible fiscal-year-end close ÷ reported annual EPS. This is retrospective annual P/E, not TTM or forward P/E. Why we use annual data. Missing or non-positive EPS and missing eligible prices produce unavailable ratios.

Explore the P/E chart and optional reference lines · How P/E history is calculated.

Complete annual P/E history (6 fiscal periods)

Full stored fiscal-year-end P/E history, independent of the selected chart window. Ratios in ×; prices in USD.
Fiscal end	Price date	Close	Price basis	Basic P/E	Diluted P/E	EPS filings
2025-12-31	2025-12-26	13.06	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-02-26) Diluted EPS (2026-02-26)
2024-12-31	2024-12-27	6.84	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-02-26) Diluted EPS (2026-02-26)
2023-12-31	2023-12-29	3.66	Adjusted close	Unavailable	Unavailable	Basic EPS (2025-03-06) Diluted EPS (2025-03-06)
2022-12-31	2022-12-30	2.20	Adjusted close	Unavailable	Unavailable	Basic EPS (2024-02-28) Diluted EPS (2024-02-28)
2021-12-31	2021-12-31	20.70	Adjusted close	Unavailable	Unavailable	Basic EPS (2023-03-09) Diluted EPS (2023-03-09)
2020-12-31	Unavailable	Unavailable	Unavailable	Unavailable	Unavailable	Source unavailable

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