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Sana Biotechnology, Inc. (SANA)

Historical prices through 2026-10-08Latest fiscal period 2025-12-31

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Sana Biotechnology, Inc. (SANA) · Nasdaq · USD · Sector unavailable · CIK 0001770121

Annual coverage: 2019-12-31–2025-12-31 (7 periods). Financial snapshot built 2026-10-09.

SANA annual financial history

All stored annual observations, independent of the chart window. Per-share amounts in USD. Unavailable values are not zero.

See the calculation and limitations.

Annual EPS, cash flow, dividends, and fiscal-year dividend yield for Sana Biotechnology, Inc.
Fiscal year / end	Basic EPS	Diluted EPS	FCF / share	Dividends / share	Fiscal-year dividend yield	Filing sources
2025 2025-12-31	-0.96	-0.96	-0.57	Unavailable	Unavailable	Basic EPS (2026-03-03) Diluted EPS (2026-03-03) Operating cash flow (2026-03-03) · Capex (2026-03-03)
2024 2024-12-31	-1.16	-1.16	-1.11	Unavailable	Unavailable	Basic EPS (2026-03-03) Diluted EPS (2026-03-03) Operating cash flow (2026-03-03) · Capex (2026-03-03)
2023 2023-12-31	-1.46	-1.46	-1.41	Unavailable	Unavailable	Basic EPS (2026-03-03) Diluted EPS (2026-03-03) Operating cash flow (2026-03-03) · Capex (2026-03-03)
2022 2022-12-31	-1.43	-1.43	-1.65	Unavailable	Unavailable	Basic EPS (2025-03-17) Diluted EPS (2025-03-17) Operating cash flow (2025-03-17) · Capex (2025-03-17)
2021 2021-12-31	-2.14	-2.14	-1.69	Unavailable	Unavailable	Basic EPS (2024-02-29) Diluted EPS (2024-02-29) Operating cash flow (2024-02-29) · Capex (2024-02-29)
2020 2020-12-31	-21.92	-21.92	-12.44	Unavailable	Unavailable	Basic EPS (2023-03-16) Diluted EPS (2023-03-16) Operating cash flow (2023-03-16) · Capex (2023-03-16)
2019 2019-12-31	Unavailable	Unavailable	Unavailable	Unavailable	Unavailable	Operating cash flow (2022-03-16) · Capex (2022-03-16)

Annual per-share context (USD/share)

Complete annual history, independent of chart loading and range. Revenue/share is annual revenue per average diluted share. Debt/share is borrowings per year-end common share, excluding leases. Missing inputs remain unavailable. Metric definitions.

Fiscal end	Revenue / share	Total debt / share	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 253234000; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 266732000 averageDilutedShares (2026-03-03) periodEndShares (2026-03-03)
2024-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 230891000; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 223923000 averageDilutedShares (2026-03-03) periodEndShares (2026-03-03)
2023-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 194541000; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 197857000 averageDilutedShares (2026-03-03) periodEndShares (2025-03-17)
2022-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 188344000; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 191022000 averageDilutedShares (2025-03-17) periodEndShares (2024-02-29)
2021-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 166433000; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 184929000 averageDilutedShares (2024-02-29) periodEndShares (2023-03-16)
2020-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: 13014000; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 16170000 averageDilutedShares (2023-03-16) periodEndShares (2022-03-16)
2019-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: No positive common shares on the exact fiscal-end date Source unavailable

Annual returns and cash generation (%)

Complete annual history, independent of chart loading and range. FCF margin and FCF / net income use matching annual totals. ROCE uses positive exact opening and closing capital-employed bases. Inputs, scopes and unavailable reasons are disclosed below. Missing inputs remain unavailable. Metric definitions.

Fiscal end	FCF margin (%)	FCF / net income (%)	ROCE (%)	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	-63.07	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-144766000,"capex":{"accession":"0001193125-26-088215","end":"2025-12-31","filed":"2026-03-03","form":"10-K","start":"2025-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-088215","end":"2025-12-31","filed":"2026-03-03","form":"10-K","start":"2025-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-244166000,"tag":"ProfitLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"operatingIncome":{"value":-250319000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingAssets":{"value":501020000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingCurrentLiabilities":{"value":45433000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingCapitalEmployed":{"value":455587000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":250504000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingTotalEquity":{"value":250504000,"inputNames":["openingParentEquity","openingAssets","openingLiabilities"]},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":250516000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingCash":{"value":127566000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingCommonEquity":{"value":250504000,"inputNames":["openingParentEquity","openingPreferredShares"]},"closingAssets":{"value":416890000,"tag":"Assets","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCurrentLiabilities":{"value":78726000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCapitalEmployed":{"value":338164000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":160884000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingTotalEquity":{"value":160884000,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":256006000,"tag":"Liabilities","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCash":{"value":71870000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2025-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCommonEquity":{"value":160884000,"inputNames":["closingParentEquity","closingPreferredShares"]},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-244166000,"tag":"NetIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":396875500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":205694000,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -63.07242447568569 fcfMargin component 1 (2026-03-03) · fcfMargin component 2 (2026-03-03) cashConversion component 1 (2026-03-03) · cashConversion component 2 (2026-03-03) · cashConversion component 3 (2026-03-03) roce component 1 (2026-03-03) · roce component 2 (2026-03-03) · roce component 3 (2026-03-03) · roce component 4 (2026-03-03) · roce component 5 (2026-03-03)
2024-12-31	Unavailable	Unavailable	-57.03	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-256583000,"capex":{"accession":"0001193125-26-088215","end":"2024-12-31","filed":"2026-03-03","form":"10-K","start":"2024-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-088215","end":"2024-12-31","filed":"2026-03-03","form":"10-K","start":"2024-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-266759000,"tag":"ProfitLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"operatingIncome":{"value":-272723000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingAssets":{"value":565299000,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingCurrentLiabilities":{"value":64487000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingCapitalEmployed":{"value":500812000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":287506000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":277793000,"tag":"Liabilities","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingCash":{"value":133517000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2023-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":501020000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCurrentLiabilities":{"value":45433000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCapitalEmployed":{"value":455587000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":250504000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingTotalEquity":{"value":250504000,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":250516000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCash":{"value":127566000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"closingCommonEquity":{"value":250504000,"inputNames":["closingParentEquity","closingPreferredShares"]},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-266759000,"tag":"NetIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":478199500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -57.03121814221889 fcfMargin component 1 (2026-03-03) · fcfMargin component 2 (2026-03-03) cashConversion component 1 (2026-03-03) · cashConversion component 2 (2026-03-03) · cashConversion component 3 (2026-03-03) roce component 1 (2026-03-03) · roce component 2 (2025-03-17) · roce component 3 (2025-03-17) · roce component 4 (2026-03-03) · roce component 5 (2026-03-03)
2023-12-31	Unavailable	Unavailable	-48.37	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-273614000,"capex":{"accession":"0001193125-26-088215","end":"2023-12-31","filed":"2026-03-03","form":"10-K","start":"2023-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-088215","end":"2023-12-31","filed":"2026-03-03","form":"10-K","start":"2023-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-283255000,"tag":"ProfitLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"operatingIncome":{"value":-293141000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingAssets":{"value":822720000,"tag":"Assets","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"openingCurrentLiabilities":{"value":111504000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"openingCapitalEmployed":{"value":711216000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":499315000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2026-03-03","accession":"0001193125-26-088215","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":323405000,"tag":"Liabilities","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"openingCash":{"value":176765000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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2022-12-31	Unavailable	Unavailable	-31.30	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-310926000,"capex":{"accession":"0000950170-25-040254","end":"2022-12-31","filed":"2025-03-17","form":"10-K","start":"2022-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0000950170-25-040254","end":"2022-12-31","filed":"2025-03-17","form":"10-K","start":"2022-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-269476000,"tag":"ProfitLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"operatingIncome":{"value":-272564000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingAssets":{"value":1129407000,"tag":"Assets","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"openingCurrentLiabilities":{"value":99235000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"openingCapitalEmployed":{"value":1030172000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":728502000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2021-12-31","filed":"2025-03-17","accession":"0000950170-25-040254","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":400905000,"tag":"Liabilities","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"openingCash":{"value":253029000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2021-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -31.30422398684268 fcfMargin component 1 (2025-03-17) · fcfMargin component 2 (2025-03-17) cashConversion component 1 (2025-03-17) · cashConversion component 2 (2025-03-17) · cashConversion component 3 (2025-03-17) roce component 1 (2025-03-17) · roce component 2 (2023-03-16) · roce component 3 (2023-03-16) · roce component 4 (2024-02-29) · roce component 5 (2024-02-29)
2021-12-31	Unavailable	Unavailable	-41.28	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-280916000,"capex":{"accession":"0000950170-24-023119","end":"2021-12-31","filed":"2024-02-29","form":"10-K","start":"2021-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0000950170-24-023119","end":"2021-12-31","filed":"2024-02-29","form":"10-K","start":"2021-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-355928000,"tag":"ProfitLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"operatingIncome":{"value":-356909000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"openingAssets":{"value":730296000,"tag":"Assets","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"openingCurrentLiabilities":{"value":31451000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"openingCapitalEmployed":{"value":698845000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":-421184000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2020-12-31","filed":"2024-02-29","accession":"0000950170-24-023119","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":298583000,"tag":"Liabilities","unit":"USD","start":null,"end":"2020-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"openingCash":{"value":124806000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2020-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -41.284614321316674 fcfMargin component 1 (2024-02-29) · fcfMargin component 2 (2024-02-29) cashConversion component 1 (2024-02-29) · cashConversion component 2 (2024-02-29) · cashConversion component 3 (2024-02-29) roce component 1 (2024-02-29) · roce component 2 (2022-03-16) · roce component 3 (2022-03-16) · roce component 4 (2023-03-16) · roce component 5 (2023-03-16)
2020-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-161854000,"capex":{"accession":"0001564590-23-003798","end":"2020-12-31","filed":"2023-03-16","form":"10-K","start":"2020-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001564590-23-003798","end":"2020-12-31","filed":"2023-03-16","form":"10-K","start":"2020-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-285305000,"tag":"ProfitLoss","unit":"USD","start":"2020-01-01","end":"2020-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"operatingIncome":{"value":-286149000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2020-01-01","end":"2020-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2019-12-31"},"openingParentEquity":{"value":-142542000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2019-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2019-12-31 fcfMargin component 1 (2023-03-16) · fcfMargin component 2 (2023-03-16) cashConversion component 1 (2023-03-16) · cashConversion component 2 (2023-03-16) · cashConversion component 3 (2023-03-16) roce component 1 (2023-03-16) · roce component 2 (2022-03-16) · roce component 3 (2022-03-16)
2019-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-111642000,"capex":{"accession":"0001564590-22-010539","end":"2019-12-31","filed":"2022-03-16","form":"10-K","start":"2019-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001564590-22-010539","end":"2019-12-31","filed":"2022-03-16","form":"10-K","start":"2019-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-130778000,"tag":"ProfitLoss","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"operatingIncome":{"value":-141152000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2018-12-31"},"openingParentEquity":{"value":-13188000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2018-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2018-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCapitalEmployed":{"value":null,"inputNames":["closingAssets","closingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2019-12-31"},"closingParentEquity":{"value":-142542000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2019-12-31","filed":"2023-03-16","accession":"0001564590-23-003798","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2019-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-130778000,"tag":"NetIncomeLoss","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":-7547000,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"pretaxIncome":{"value":-138325000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2019-01-01","end":"2019-12-31","filed":"2022-03-16","accession":"0001564590-22-010539","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Positive pretax income required"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Positive pretax income required"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed, closingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2018-12-31; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2019-12-31 fcfMargin component 1 (2022-03-16) · fcfMargin component 2 (2022-03-16) cashConversion component 1 (2022-03-16) · cashConversion component 2 (2022-03-16) · cashConversion component 3 (2022-03-16) roce component 1 (2022-03-16)

Annual operating facts

Complete annual history, independent of chart loading and range. Operating margin is operating profit as a percentage of revenue; net margin is consolidated net profit as a percentage of revenue. Negative margins show losses. Missing inputs remain unavailable. Metric definitions.

Fiscal end	Revenue (USD)	Operating margin (%)	Net margin (%)	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -250319000; netIncome: -244166000 operatingIncome (2026-03-03) netIncome (2026-03-03)
2024-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -272723000; netIncome: -266759000 operatingIncome (2026-03-03) netIncome (2026-03-03)
2023-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -293141000; netIncome: -283255000 operatingIncome (2026-03-03) netIncome (2026-03-03)
2022-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -272564000; netIncome: -269476000 operatingIncome (2025-03-17) netIncome (2025-03-17)
2021-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -356909000; netIncome: -355928000 operatingIncome (2024-02-29) netIncome (2024-02-29)
2020-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -286149000; netIncome: -285305000 operatingIncome (2023-03-16) netIncome (2023-03-16)
2019-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -141152000; netIncome: -130778000 operatingIncome (2022-03-16) netIncome (2022-03-16)

Sana Biotechnology, Inc. (SANA) P/E ratio history

The interactive P/E chart contains all 297 stored weekly price points (2021-02-05–2026-10-08); 0 have an eligible basic or diluted ratio. Annual EPS is carried forward from its fiscal end. Use the P/E range bar or any other chart range bar to change all five chart windows.

Fiscal-year-end snapshots

No positive annual EPS with an eligible fiscal-year-end price is available in this snapshot.

Annual P/E = eligible fiscal-year-end close ÷ reported annual EPS. This is retrospective annual P/E, not TTM or forward P/E. Why we use annual data. Missing or non-positive EPS and missing eligible prices produce unavailable ratios.

Explore the P/E chart and optional reference lines · How P/E history is calculated.

Complete annual P/E history (7 fiscal periods)

Full stored fiscal-year-end P/E history, independent of the selected chart window. Ratios in ×; prices in USD.
Fiscal end	Price date	Close	Price basis	Basic P/E	Diluted P/E	EPS filings
2025-12-31	2025-12-26	4.41	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-03-03) Diluted EPS (2026-03-03)
2024-12-31	2024-12-27	1.61	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-03-03) Diluted EPS (2026-03-03)
2023-12-31	2023-12-29	4.08	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-03-03) Diluted EPS (2026-03-03)
2022-12-31	2022-12-30	3.95	Adjusted close	Unavailable	Unavailable	Basic EPS (2025-03-17) Diluted EPS (2025-03-17)
2021-12-31	2021-12-31	15.48	Adjusted close	Unavailable	Unavailable	Basic EPS (2024-02-29) Diluted EPS (2024-02-29)
2020-12-31	Unavailable	Unavailable	Unavailable	Unavailable	Unavailable	Basic EPS (2023-03-16) Diluted EPS (2023-03-16)
2019-12-31	Unavailable	Unavailable	Unavailable	Unavailable	Unavailable	Source unavailable

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