The interactive chart is unavailable. The financial history below remains available.
Loading stock chart…
Septerna, Inc. (SEPN)
Price & fundamentals
Compound Annual Growth Rate(CAGR)
Historical valuation multiples
Ratio observations in the selected window
| Price date | EPS fiscal end | Basic P/E (×) | Diluted P/E (×) | P/S (×) | P/FCF (×) |
|---|
Profit margins
Calculation inputs, filings & unavailable observations
Yield, cash conversion & capital returns
Calculation inputs, filings & unavailable observations
Price & growth-based reference
Annual change in the selected reference metric
YEAR-OVER-YEAR
Annual metric change
Change from the previous reported fiscal year
Annual data and sources
Septerna, Inc. (SEPN) · Nasdaq · USD · Sector unavailable · CIK 0001984086
Annual coverage: 2023-12-31–2025-12-31 (3 periods). Financial snapshot built 2026-10-09.
SEPN annual financial history
All stored annual observations, independent of the chart window. Per-share amounts in USD. Unavailable values are not zero.
See the calculation and limitations.
| Fiscal year / end | Basic EPS | Diluted EPS | FCF / share | Dividends / share | Fiscal-year dividend yield | Filing sources |
|---|---|---|---|---|---|---|
| 2025 2025-12-31 | -1.10 | -1.10 | 2.48 | Unavailable | Unavailable | Basic EPS (2026-03-09) Diluted EPS (2026-03-09) Operating cash flow (2026-03-09) · Capex (2026-03-09) |
| 2024 2024-12-31 | -7.26 | -7.26 | -7.03 | Unavailable | Unavailable | Basic EPS (2026-03-09) Diluted EPS (2026-03-09) Operating cash flow (2026-03-09) · Capex (2026-03-09) |
| 2023 2023-12-31 | 0.29 | 0.29 | -19.11 | Unavailable | Unavailable | Basic EPS (2025-03-27) Diluted EPS (2025-03-27) Operating cash flow (2025-03-27) · Capex (2025-03-27) |
Annual per-share context (USD/share)
Complete annual history, independent of chart loading and range. Revenue/share is annual revenue per average diluted share. Debt/share is borrowings per year-end common share, excluding leases. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | Revenue / share | Total debt / share | Inputs & filing sources |
|---|---|---|---|
| 2025-12-31 | 1.04 | Unavailable | Inputs & filingsrevenue: 45951000; averageDilutedShares: 44258338; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 44806272 revenue (2026-03-09)averageDilutedShares (2026-03-09) periodEndShares (2026-03-09) |
| 2024-12-31 | 0.11 | Unavailable | Inputs & filingsrevenue: 1075000; averageDilutedShares: 9891126; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 44422505 revenue (2026-03-09)averageDilutedShares (2026-03-09) periodEndShares (2026-03-09) |
| 2023-12-31 | 0.07 | Unavailable | Inputs & filingsrevenue: 151000; averageDilutedShares: 2177124; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 3168134 revenue (2025-03-27)averageDilutedShares (2025-03-27) periodEndShares (2025-03-27) |
Annual returns and cash generation (%)
Complete annual history, independent of chart loading and range. FCF margin and FCF / net income use matching annual totals. ROCE uses positive exact opening and closing capital-employed bases. Inputs, scopes and unavailable reasons are disclosed below. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | FCF margin (%) | FCF / net income (%) | ROCE (%) | Inputs & filing sources |
|---|---|---|---|---|
| 2025-12-31 | 238.67 | Unavailable | -14.33 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":109671000,"capex":{"accession":"0001193125-26-098507","end":"2025-12-31","filed":"2026-03-09","form":"10-K","start":"2025-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-098507","end":"2025-12-31","filed":"2026-03-09","form":"10-K","start":"2025-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":45951000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"netIncome":{"value":-48879000,"tag":"ProfitLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"operatingIncome":{"value":-68297000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingAssets":{"value":456554000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingCurrentLiabilities":{"value":12849000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingCapitalEmployed":{"value":443705000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":420047000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingTotalEquity":{"value":420047000,"inputNames":["openingParentEquity","openingAssets","openingLiabilities"]},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":36507000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingCash":{"value":238196000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingCommonEquity":{"value":420047000,"inputNames":["openingParentEquity","openingPreferredShares"]},"closingAssets":{"value":596187000,"tag":"Assets","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCurrentLiabilities":{"value":86931000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCapitalEmployed":{"value":509256000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":381926000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingTotalEquity":{"value":381926000,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":214261000,"tag":"Liabilities","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCash":{"value":120722000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2025-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCommonEquity":{"value":381926000,"inputNames":["closingParentEquity","closingPreferredShares"]},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-48879000,"tag":"NetIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":12000,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"pretaxIncome":{"value":-48867000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Positive pretax income required"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Positive pretax income required"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":476480500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":400986500,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: 238.66945224260627; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -14.333640096499229 fcfMargin component 1 (2026-03-09) · fcfMargin component 2 (2026-03-09) · fcfMargin component 3 (2026-03-09)cashConversion component 1 (2026-03-09) · cashConversion component 2 (2026-03-09) · cashConversion component 3 (2026-03-09) roce component 1 (2026-03-09) · roce component 2 (2026-03-09) · roce component 3 (2026-03-09) · roce component 4 (2026-03-09) · roce component 5 (2026-03-09) |
| 2024-12-31 | -6,471.91 | Unavailable | -28.48 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-69573000,"capex":{"accession":"0001193125-26-098507","end":"2024-12-31","filed":"2026-03-09","form":"10-K","start":"2024-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-098507","end":"2024-12-31","filed":"2026-03-09","form":"10-K","start":"2024-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":1075000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"netIncome":{"value":-71798000,"tag":"ProfitLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"operatingIncome":{"value":-80823000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingAssets":{"value":130867000,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingCurrentLiabilities":{"value":6914000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingCapitalEmployed":{"value":123953000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":-38374000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":20026000,"tag":"Liabilities","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingCash":{"value":88483000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":456554000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCurrentLiabilities":{"value":12849000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCapitalEmployed":{"value":443705000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":420047000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingTotalEquity":{"value":420047000,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":36507000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCash":{"value":238196000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingCommonEquity":{"value":420047000,"inputNames":["closingParentEquity","closingPreferredShares"]},"commonNetIncome":{"value":-71798000,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"incomeTaxExpense":{"value":-498000,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"pretaxIncome":{"value":-72296000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Positive pretax income required"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Positive pretax income required"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":283829000,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: -6471.906976744187; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -28.475948546483977 fcfMargin component 1 (2026-03-09) · fcfMargin component 2 (2026-03-09) · fcfMargin component 3 (2026-03-09)cashConversion component 1 (2026-03-09) · cashConversion component 2 (2026-03-09) · cashConversion component 3 (2026-03-09) roce component 1 (2026-03-09) · roce component 2 (2025-03-27) · roce component 3 (2025-03-27) · roce component 4 (2026-03-09) · roce component 5 (2026-03-09) |
| 2023-12-31 | -27,550.33 | -995.24 | Unavailable | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-41601000,"capex":{"accession":"0000950170-25-045745","end":"2023-12-31","filed":"2025-03-27","form":"10-K","start":"2023-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0000950170-25-045745","end":"2023-12-31","filed":"2025-03-27","form":"10-K","start":"2023-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":151000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"netIncome":{"value":4180000,"tag":"ProfitLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"operatingIncome":{"value":2075000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2022-12-31"},"openingParentEquity":{"value":-44201000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2022-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":130867000,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"closingCurrentLiabilities":{"value":6914000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"closingCapitalEmployed":{"value":123953000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":-38374000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":20026000,"tag":"Liabilities","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"closingCash":{"value":88483000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":567000,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"incomeTaxExpense":{"value":691000,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-03-27","accession":"0000950170-25-045745","form":"10-K"},"pretaxIncome":{"value":-48867000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2026-03-09","accession":"0001193125-26-098507","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Positive pretax income required"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Positive pretax income required"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: -27550.33112582781; cashConversion: -995.2392344497607; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2022-12-31 fcfMargin component 1 (2025-03-27) · fcfMargin component 2 (2025-03-27) · fcfMargin component 3 (2025-03-27)cashConversion component 1 (2025-03-27) · cashConversion component 2 (2025-03-27) · cashConversion component 3 (2025-03-27) roce component 1 (2025-03-27) · roce component 2 (2025-03-27) · roce component 3 (2025-03-27) |
Annual operating facts
Complete annual history, independent of chart loading and range. Operating margin is operating profit as a percentage of revenue; net margin is consolidated net profit as a percentage of revenue. Negative margins show losses. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | Revenue (USD) | Operating margin (%) | Net margin (%) | Inputs & filing sources |
|---|---|---|---|---|
| 2025-12-31 | 45,951,000.00 | -148.63 | -106.37 | Inputs & filingsrevenue: 45951000; operatingIncome: -68297000; netIncome: -48879000 revenue (2026-03-09)operatingIncome (2026-03-09) netIncome (2026-03-09) |
| 2024-12-31 | 1,075,000.00 | -7,518.42 | -6,678.88 | Inputs & filingsrevenue: 1075000; operatingIncome: -80823000; netIncome: -71798000 revenue (2026-03-09)operatingIncome (2026-03-09) netIncome (2026-03-09) |
| 2023-12-31 | 151,000.00 | 1,374.17 | 2,768.21 | Inputs & filingsrevenue: 151000; operatingIncome: 2075000; netIncome: 4180000 revenue (2025-03-27)operatingIncome (2025-03-27) netIncome (2025-03-27) |
Septerna, Inc. (SEPN) P/E ratio history
The interactive P/E chart contains all 103 stored weekly price points (2024-10-25–2026-10-08); 10 have an eligible basic or diluted ratio. Annual EPS is carried forward from its fiscal end. Use the P/E range bar or any other chart range bar to change all five chart windows.
Fiscal-year-end snapshots
No positive annual EPS with an eligible fiscal-year-end price is available in this snapshot.
Annual P/E = eligible fiscal-year-end close ÷ reported annual EPS. This is retrospective annual P/E, not TTM or forward P/E. Why we use annual data. Missing or non-positive EPS and missing eligible prices produce unavailable ratios.
Explore the P/E chart and optional reference lines · How P/E history is calculated.
Complete annual P/E history (3 fiscal periods)
| Fiscal end | Price date | Close | Price basis | Basic P/E | Diluted P/E | EPS filings |
|---|---|---|---|---|---|---|
| 2025-12-31 | 2025-12-26 | 28.62 | Adjusted close | Unavailable | Unavailable | Basic EPS (2026-03-09) Diluted EPS (2026-03-09) |
| 2024-12-31 | 2024-12-27 | 25.33 | Adjusted close | Unavailable | Unavailable | Basic EPS (2026-03-09) Diluted EPS (2026-03-09) |
| 2023-12-31 | Unavailable | Unavailable | Unavailable | Unavailable | Unavailable | Basic EPS (2025-03-27) Diluted EPS (2025-03-27) |
Did this research save you time?
I build and maintain Stock Value Lens independently. If you found it useful, a coffee helps me maintain the tools and improve data updates.