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Shuttle Pharmaceuticals Holdings, Inc. (SHPH)

Historical prices through 2026-05-08Latest fiscal period 2025-12-31

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Shuttle Pharmaceuticals Holdings, Inc. (SHPH) · Nasdaq · USD · Sector unavailable · CIK 0001757499

Annual coverage: 2021-12-31–2025-12-31 (5 periods). Financial snapshot built 2026-10-09.

Earlier snapshot retained while historical price and annual per-share adjustments are reviewed.

SHPH annual financial history

All stored annual observations, independent of the chart window. Per-share amounts in USD. Unavailable values are not zero.

See the calculation and limitations.

Annual EPS, cash flow, dividends, and fiscal-year dividend yield for Shuttle Pharmaceuticals Holdings, Inc.
Fiscal year / end	Basic EPS	Diluted EPS	FCF / share	Dividends / share	Fiscal-year dividend yield	Filing sources
2025 2025-12-31	-7.16	-7.16	Unavailable	Unavailable	Unavailable	Basic EPS (2026-03-31) Diluted EPS (2026-03-31)
2024 2024-12-31	-79.65	-82.60	Unavailable	Unavailable	Unavailable	Basic EPS (2026-03-31) Diluted EPS (2026-03-31)
2023 2023-12-31	-3.53	-3.53	-3.00	Unavailable	Unavailable	Basic EPS (2025-02-26) Diluted EPS (2025-02-26) Operating cash flow (2025-02-26) · Capex (2025-02-26)
2022 2022-12-31	-5.04	-5.04	Unavailable	Unavailable	Unavailable	Basic EPS (2024-09-04) Diluted EPS (2024-09-04)
2021 2021-12-31	-0.12	Unavailable	Unavailable	Unavailable	Unavailable	Basic EPS (2023-03-15)

Annual per-share context (USD/share)

Complete annual history, independent of chart loading and range. Revenue/share is annual revenue per average diluted share. Debt/share is borrowings per year-end common share, excluding leases. Missing inputs remain unavailable. Metric definitions.

Fiscal end	Revenue / share	Total debt / share	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: Retained price/financial basis requires review; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: Retained price/financial basis requires review Source unavailable
2024-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: Retained price/financial basis requires review; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: Retained price/financial basis requires review Source unavailable
2023-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: Retained price/financial basis requires review; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: Retained price/financial basis requires review Source unavailable
2022-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: Retained price/financial basis requires review; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: Retained price/financial basis requires review Source unavailable
2021-12-31	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; averageDilutedShares: Retained price/financial basis requires review; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: Retained price/financial basis requires review Source unavailable

Annual returns and cash generation (%)

Complete annual history, independent of chart loading and range. FCF margin and FCF / net income use matching annual totals. ROCE uses positive exact opening and closing capital-employed bases. Inputs, scopes and unavailable reasons are disclosed below. Missing inputs remain unavailable. Metric definitions.

Fiscal end	FCF margin (%)	FCF / net income (%)	ROCE (%)	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	-684.56	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-11721669,"tag":"NetIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"operatingIncome":{"value":-11916824,"tag":"OperatingIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingAssets":{"value":2506290,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingCurrentLiabilities":{"value":1533769,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingCapitalEmployed":{"value":972521,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":709152,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingTotalEquity":{"value":709152,"inputNames":["openingParentEquity","openingAssets","openingLiabilities"]},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":1797138,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingCash":{"value":1920144,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingCommonEquity":{"value":709152,"inputNames":["openingParentEquity","openingPreferredShares"]},"closingAssets":{"value":10475977,"tag":"Assets","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCurrentLiabilities":{"value":7966891,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCapitalEmployed":{"value":2509086,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":2254446,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingTotalEquity":{"value":2254446,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":8221531,"tag":"Liabilities","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCash":{"value":334005,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2025-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -684.5588258525446 cashConversion component 1 (2026-03-31) roce component 1 (2026-03-31) · roce component 2 (2026-03-31) · roce component 3 (2026-03-31) · roce component 4 (2026-03-31) · roce component 5 (2026-03-31)
2024-12-31	Unavailable	Unavailable	-261.68	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-9539875,"tag":"ProfitLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"operatingIncome":{"value":-7696170,"tag":"OperatingIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingAssets":{"value":5951736,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingCurrentLiabilities":{"value":1042237,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingCapitalEmployed":{"value":4909499,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":4055771,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":1895965,"tag":"Liabilities","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingCash":{"value":2576416,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":2506290,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCurrentLiabilities":{"value":1533769,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCapitalEmployed":{"value":972521,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":709152,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingTotalEquity":{"value":709152,"inputNames":["closingParentEquity","closingAssets","closingLiabilities"]},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":1797138,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCash":{"value":1920144,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2024-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"closingCommonEquity":{"value":709152,"inputNames":["closingParentEquity","closingPreferredShares"]},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-9144797,"tag":"NetIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-31","accession":"0001493152-26-014131","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":2941010,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -261.6845913478703 cashConversion component 1 (2025-02-26) roce component 1 (2026-03-31) · roce component 2 (2025-02-26) · roce component 3 (2025-02-26) · roce component 4 (2026-03-31) · roce component 5 (2026-03-31)
2023-12-31	Unavailable	Unavailable	-93.62	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":-5600193,"capex":{"accession":"0001493152-25-008300","end":"2023-12-31","filed":"2025-02-26","form":"10-K","start":"2023-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001493152-25-008300","end":"2023-12-31","filed":"2025-02-26","form":"10-K","start":"2023-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-6592723,"tag":"NetIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"operatingIncome":{"value":-5892382,"tag":"OperatingIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingAssets":{"value":8653545,"tag":"Assets","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingCurrentLiabilities":{"value":975676,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingCapitalEmployed":{"value":7677869,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":7677869,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":975676,"tag":"Liabilities","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingCash":{"value":8417203,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2023-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2023-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":-6592723,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":-6592723,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":6293684,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{"roe":{"commonNetIncome":{"value":-6592723,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"averageCommonEquity":{"value":5866820,"inputNames":["openingCommonEquity","closingCommonEquity"]},"openingCommonEquity":{"value":7677869,"inputNames":["openingParentEquity","openingPreferredShares"]},"openingParentEquity":{"value":7677869,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingCommonEquity":{"value":4055771,"inputNames":["closingParentEquity","closingPreferredShares"]},"closingParentEquity":{"value":4055771,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2023-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"}}}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -93.62373452496186 fcfMargin component 1 (2025-02-26) · fcfMargin component 2 (2025-02-26) cashConversion component 1 (2025-02-26) · cashConversion component 2 (2025-02-26) · cashConversion component 3 (2025-02-26) roce component 1 (2025-02-26) · roce component 2 (2024-09-04) · roce component 3 (2024-09-04) · roce component 4 (2025-02-26) · roce component 5 (2025-02-26)
2022-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":1687508,"tag":"ProfitLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-03-21","accession":"0001493152-24-010822","form":"10-K"},"operatingIncome":{"value":-2343826,"tag":"OperatingIncomeLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingAssets":{"value":651641,"tag":"Assets","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingCurrentLiabilities":{"value":2217331,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingCapitalEmployed":{"value":-1565690,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":-1764220,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2021-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":2279773,"tag":"Liabilities","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingCash":{"value":504749,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2021-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":1213,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":8653545,"tag":"Assets","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingCurrentLiabilities":{"value":975676,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingCapitalEmployed":{"value":7677869,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":7677869,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-02-26","accession":"0001493152-25-008300","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":975676,"tag":"Liabilities","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingCash":{"value":8417203,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2022-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":-6747137,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":-4996069,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; nonpositive: openingCapitalEmployed cashConversion component 1 (2024-03-21) roce component 1 (2024-09-04) · roce component 2 (2023-03-15) · roce component 3 (2023-03-15) · roce component 4 (2024-09-04) · roce component 5 (2024-09-04)
2021-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings Calculation inputs: {"original":{"fcfTotal":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-1152134,"tag":"NetIncomeLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"operatingIncome":{"value":-1742992,"tag":"OperatingIncomeLoss","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2020-12-31"},"openingParentEquity":{"value":-1690296,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2020-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2020-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":651641,"tag":"Assets","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"closingCurrentLiabilities":{"value":2217331,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"closingCapitalEmployed":{"value":-1565690,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":-1764220,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2021-12-31","filed":"2024-09-04","accession":"0001493152-24-034898","form":"10-K/A"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":2279773,"tag":"Liabilities","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"closingCash":{"value":504749,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2021-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":1213,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":-1255196,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"incomeTaxExpense":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"pretaxIncome":{"value":-1152134,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2021-01-01","end":"2021-12-31","filed":"2023-03-15","accession":"0001493152-23-007686","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed; nonpositive: closingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2020-12-31 cashConversion component 1 (2023-03-15) roce component 1 (2023-03-15) · roce component 2 (2023-03-15) · roce component 3 (2023-03-15)

Annual operating facts

Complete annual history, independent of chart loading and range. Operating margin is operating profit as a percentage of revenue; net margin is consolidated net profit as a percentage of revenue. Negative margins show losses. Missing inputs remain unavailable. Metric definitions.

Fiscal end	Revenue (USD)	Operating margin (%)	Net margin (%)	Inputs & filing sources
2025-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -11916824; netIncome: -11721669 operatingIncome (2026-03-31) netIncome (2026-03-31)
2024-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -7696170; netIncome: -9539875 operatingIncome (2026-03-31) netIncome (2025-02-26)
2023-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -5892382; netIncome: -6592723 operatingIncome (2025-02-26) netIncome (2025-02-26)
2022-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -2343826; netIncome: 1687508 operatingIncome (2024-09-04) netIncome (2024-03-21)
2021-12-31	Unavailable	Unavailable	Unavailable	Inputs & filings revenue: No unambiguous matching annual USD fact; operatingIncome: -1742992; netIncome: -1152134 operatingIncome (2023-03-15) netIncome (2023-03-15)

Shuttle Pharmaceuticals Holdings, Inc. (SHPH) P/E ratio history

The interactive P/E chart contains all 193 stored weekly price points (2022-09-02–2026-05-08); 0 have an eligible basic or diluted ratio. Annual EPS is carried forward from its fiscal end. Use the P/E range bar or any other chart range bar to change all five chart windows.

Fiscal-year-end snapshots

No positive annual EPS with an eligible fiscal-year-end price is available in this snapshot.

Annual P/E = eligible fiscal-year-end close ÷ reported annual EPS. This is retrospective annual P/E, not TTM or forward P/E. Why we use annual data. Missing or non-positive EPS and missing eligible prices produce unavailable ratios.

Explore the P/E chart and optional reference lines · How P/E history is calculated.

Complete annual P/E history (5 fiscal periods)

Full stored fiscal-year-end P/E history, independent of the selected chart window. Ratios in ×; prices in USD.
Fiscal end	Price date	Close	Price basis	Basic P/E	Diluted P/E	EPS filings
2025-12-31	2025-12-26	1.87	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-03-31) Diluted EPS (2026-03-31)
2024-12-31	2024-12-27	18.53	Adjusted close	Unavailable	Unavailable	Basic EPS (2026-03-31) Diluted EPS (2026-03-31)
2023-12-31	2023-12-29	91.00	Adjusted close	Unavailable	Unavailable	Basic EPS (2025-02-26) Diluted EPS (2025-02-26)
2022-12-31	2022-12-30	392.00	Adjusted close	Unavailable	Unavailable	Basic EPS (2024-09-04) Diluted EPS (2024-09-04)
2021-12-31	Unavailable	Unavailable	Unavailable	Unavailable	Unavailable	Basic EPS (2023-03-15) Source unavailable

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