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Silence Therapeutics plc (SLN)
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| Price date | EPS fiscal end | Basic P/E (×) | Diluted P/E (×) | P/S (×) | P/FCF (×) |
|---|
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Silence Therapeutics plc (SLN) · Nasdaq · USD · Sector unavailable · CIK 0001479615
Annual coverage: 2022-12-31–2025-12-31 (4 periods). Financial snapshot built 2026-10-09.
SLN annual financial history
All stored annual observations, independent of the chart window. Per-share amounts in USD. Unavailable values are not zero.
See the calculation and limitations.
| Fiscal year / end | Basic EPS | Diluted EPS | FCF / share | Dividends / share | Fiscal-year dividend yield | Filing sources |
|---|---|---|---|---|---|---|
| 2025 2025-12-31 | -0.63 | -0.63 | -0.44 | Unavailable | Unavailable | Basic EPS (2026-03-05) Diluted EPS (2026-03-05) Operating cash flow (2026-03-05) · Capex (2026-03-05) |
| 2024 2024-12-31 | -0.33 | -0.33 | -0.49 | Unavailable | Unavailable | Basic EPS (2026-03-05) Diluted EPS (2026-03-05) Operating cash flow (2026-03-05) · Capex (2026-03-05) |
| 2023 2023-12-31 | -0.49 | -0.49 | -0.44 | Unavailable | Unavailable | Basic EPS (2025-02-27) Diluted EPS (2025-02-27) Operating cash flow (2025-02-27) · Capex (2025-02-27) |
| 2022 2022-12-31 | -0.52 | -0.52 | -0.59 | Unavailable | Unavailable | Basic EPS (2025-02-27) Diluted EPS (2025-02-27) Operating cash flow (2025-02-27) · Capex (2025-02-27) |
Annual per-share context (USD/share)
Complete annual history, independent of chart loading and range. Revenue/share is annual revenue per average diluted share. Debt/share is borrowings per year-end common share, excluding leases. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | Revenue / share | Total debt / share | Inputs & filing sources |
|---|---|---|---|
| 2025-12-31 | 0.00 | Unavailable | Inputs & filingsrevenue: 559000; averageDilutedShares: 141694702; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 141701848 revenue (2026-03-05)averageDilutedShares (2026-03-05) periodEndShares (2026-03-05) |
| 2024-12-31 | 0.31 | Unavailable | Inputs & filingsrevenue: 43258000; averageDilutedShares: 138752224; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 141674074 revenue (2026-03-05)averageDilutedShares (2026-03-05) periodEndShares (2026-03-05) |
| 2023-12-31 | 0.28 | Unavailable | Inputs & filingsrevenue: 31643000; averageDilutedShares: 111277250; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 118846966 revenue (2026-03-05)averageDilutedShares (2025-02-27) periodEndShares (2025-02-27) |
| 2022-12-31 | 0.22 | Unavailable | Inputs & filingsrevenue: 21655000; averageDilutedShares: 96584512; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 107808472 revenue (2025-02-27)averageDilutedShares (2025-02-27) periodEndShares (2025-02-27) |
Annual returns and cash generation (%)
Complete annual history, independent of chart loading and range. FCF margin and FCF / net income use matching annual totals. ROCE uses positive exact opening and closing capital-employed bases. Inputs, scopes and unavailable reasons are disclosed below. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | FCF margin (%) | FCF / net income (%) | ROCE (%) | Inputs & filing sources |
|---|---|---|---|---|
| 2025-12-31 | -11,149.55 | Unavailable | -59.99 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-62326000,"capex":{"accession":"0001193125-26-092591","end":"2025-12-31","filed":"2026-03-05","form":"10-K","start":"2025-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-092591","end":"2025-12-31","filed":"2026-03-05","form":"10-K","start":"2025-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":559000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"netIncome":{"value":-88612000,"tag":"ProfitLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"operatingIncome":{"value":-91077000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2025-01-01","end":"2025-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingAssets":{"value":202635000,"tag":"Assets","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingCurrentLiabilities":{"value":16822000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingCapitalEmployed":{"value":185813000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":134023000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingTotalEquity":{"value":134023000,"inputNames":["openingParentEquity","openingAssets","openingLiabilities"]},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":68612000,"tag":"Liabilities","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingCash":{"value":121330000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: -11149.552772808585; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -59.98972474163653 fcfMargin component 1 (2026-03-05) · fcfMargin component 2 (2026-03-05) · fcfMargin component 3 (2026-03-05)cashConversion component 1 (2026-03-05) · cashConversion component 2 (2026-03-05) · cashConversion component 3 (2026-03-05) roce component 1 (2026-03-05) · roce component 2 (2026-03-05) · roce component 3 (2026-03-05) · roce component 4 (2026-03-05) · roce component 5 (2026-03-05) |
| 2024-12-31 | -156.85 | Unavailable | -44.76 | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-67851000,"capex":{"accession":"0001193125-26-092591","end":"2024-12-31","filed":"2026-03-05","form":"10-K","start":"2024-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001193125-26-092591","end":"2024-12-31","filed":"2026-03-05","form":"10-K","start":"2024-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":43258000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"netIncome":{"value":-45309000,"tag":"ProfitLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"operatingIncome":{"value":-63319000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2024-01-01","end":"2024-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingAssets":{"value":119448000,"tag":"Assets","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingCurrentLiabilities":{"value":22336000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingCapitalEmployed":{"value":97112000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":21993000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2023-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":97455000,"tag":"Liabilities","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingCash":{"value":68789000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2023-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: -156.85191178510334; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -44.760272156932054 fcfMargin component 1 (2026-03-05) · fcfMargin component 2 (2026-03-05) · fcfMargin component 3 (2026-03-05)cashConversion component 1 (2026-03-05) · cashConversion component 2 (2026-03-05) · cashConversion component 3 (2026-03-05) roce component 1 (2026-03-05) · roce component 2 (2025-02-27) · roce component 3 (2025-02-27) · roce component 4 (2026-03-05) · roce component 5 (2026-03-05) |
| 2023-12-31 | -156.49 | Unavailable | Unavailable | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-49518000,"capex":{"accession":"0000950170-25-029129","end":"2023-12-31","filed":"2025-02-27","form":"10-K","start":"2023-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0000950170-25-029129","end":"2023-12-31","filed":"2025-02-27","form":"10-K","start":"2023-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":31643000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2026-03-05","accession":"0001193125-26-092591","form":"10-K"},"netIncome":{"value":-54228000,"tag":"ProfitLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"operatingIncome":{"value":-64383000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2023-01-01","end":"2023-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2022-12-31"},"openingParentEquity":{"value":27221000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: -156.48958695446072; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2022-12-31 fcfMargin component 1 (2025-02-27) · fcfMargin component 2 (2025-02-27) · fcfMargin component 3 (2025-02-27)cashConversion component 1 (2025-02-27) · cashConversion component 2 (2025-02-27) · cashConversion component 3 (2025-02-27) roce component 1 (2025-02-27) · roce component 2 (2025-02-27) · roce component 3 (2025-02-27) |
| 2022-12-31 | -264.22 | Unavailable | Unavailable | Inputs & filingsCalculation inputs: {"original":{"fcfTotal":{"value":-57217000,"capex":{"accession":"0000950170-25-029129","end":"2022-12-31","filed":"2025-02-27","form":"10-K","start":"2022-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0000950170-25-029129","end":"2022-12-31","filed":"2025-02-27","form":"10-K","start":"2022-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":21655000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"netIncome":{"value":-50334000,"tag":"ProfitLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"operatingIncome":{"value":-61040000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2021-12-31"},"openingParentEquity":{"value":12374000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2021-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2021-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCapitalEmployed":{"value":null,"inputNames":["closingAssets","closingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2022-12-31"},"closingParentEquity":{"value":27221000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCash":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2022-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"parentNetIncome":{"value":-50334000,"tag":"NetIncomeLoss","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"preferredDividends":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"incomeTaxExpense":{"value":688000,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"pretaxIncome":{"value":-49646000,"tag":"IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest","unit":"USD","start":"2022-01-01","end":"2022-12-31","filed":"2025-02-27","accession":"0000950170-25-029129","form":"10-K"},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Positive pretax income required"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Positive pretax income required"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: -264.22073424151466; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed, closingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2021-12-31; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2022-12-31 fcfMargin component 1 (2025-02-27) · fcfMargin component 2 (2025-02-27) · fcfMargin component 3 (2025-02-27)cashConversion component 1 (2025-02-27) · cashConversion component 2 (2025-02-27) · cashConversion component 3 (2025-02-27) roce component 1 (2025-02-27) |
Annual operating facts
Complete annual history, independent of chart loading and range. Operating margin is operating profit as a percentage of revenue; net margin is consolidated net profit as a percentage of revenue. Negative margins show losses. Missing inputs remain unavailable. Metric definitions.
| Fiscal end | Revenue (USD) | Operating margin (%) | Net margin (%) | Inputs & filing sources |
|---|---|---|---|---|
| 2025-12-31 | 559,000.00 | -16,292.84 | -15,851.88 | Inputs & filingsrevenue: 559000; operatingIncome: -91077000; netIncome: -88612000 revenue (2026-03-05)operatingIncome (2026-03-05) netIncome (2026-03-05) |
| 2024-12-31 | 43,258,000.00 | -146.38 | -104.74 | Inputs & filingsrevenue: 43258000; operatingIncome: -63319000; netIncome: -45309000 revenue (2026-03-05)operatingIncome (2026-03-05) netIncome (2026-03-05) |
| 2023-12-31 | 31,643,000.00 | -203.47 | -171.37 | Inputs & filingsrevenue: 31643000; operatingIncome: -64383000; netIncome: -54228000 revenue (2026-03-05)operatingIncome (2025-02-27) netIncome (2025-02-27) |
| 2022-12-31 | 21,655,000.00 | -281.87 | -232.44 | Inputs & filingsrevenue: 21655000; operatingIncome: -61040000; netIncome: -50334000 revenue (2025-02-27)operatingIncome (2025-02-27) netIncome (2025-02-27) |
Silence Therapeutics plc (SLN) P/E ratio history
The interactive P/E chart contains all 314 stored weekly price points (2020-09-16–2026-10-08); 0 have an eligible basic or diluted ratio. Annual EPS is carried forward from its fiscal end. Use the P/E range bar or any other chart range bar to change all five chart windows.
Fiscal-year-end snapshots
No positive annual EPS with an eligible fiscal-year-end price is available in this snapshot.
Annual P/E = eligible fiscal-year-end close ÷ reported annual EPS. This is retrospective annual P/E, not TTM or forward P/E. Why we use annual data. Missing or non-positive EPS and missing eligible prices produce unavailable ratios.
Explore the P/E chart and optional reference lines · How P/E history is calculated.
Complete annual P/E history (4 fiscal periods)
| Fiscal end | Price date | Close | Price basis | Basic P/E | Diluted P/E | EPS filings |
|---|---|---|---|---|---|---|
| 2025-12-31 | 2025-12-26 | 6.20 | Adjusted close | Unavailable | Unavailable | Basic EPS (2026-03-05) Diluted EPS (2026-03-05) |
| 2024-12-31 | 2024-12-27 | 7.10 | Adjusted close | Unavailable | Unavailable | Basic EPS (2026-03-05) Diluted EPS (2026-03-05) |
| 2023-12-31 | 2023-12-29 | 17.37 | Adjusted close | Unavailable | Unavailable | Basic EPS (2025-02-27) Diluted EPS (2025-02-27) |
| 2022-12-31 | 2022-12-30 | 15.25 | Adjusted close | Unavailable | Unavailable | Basic EPS (2025-02-27) Diluted EPS (2025-02-27) |
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