Spyre Therapeutics, Inc. (SYRE)

revenue: 0; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 78189811

revenue: 0; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 60257023

revenue: 886000; averageDilutedShares: 6897065; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 36057109

revenue: 2329000; averageDilutedShares: 3371231; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 2614014

revenue: 18739000; averageDilutedShares: 2629784; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 49355130

revenue: 0; averageDilutedShares: 53371730; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 47959086

revenue: 0; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 29084437

revenue: 3888000; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 24140097

revenue: 5205000; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 16670188

revenue: 4628000; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 13430833

revenue: No unambiguous matching annual USD fact; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: 71946.92

revenue: No unambiguous matching annual USD fact; averageDilutedShares: No positive shares on the exact annual duration; totalDebt: No supported complete debt aggregate or non-overlapping borrowing components; leases excluded; periodEndShares: No positive common shares on the exact fiscal-end date

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fcfMargin: Stored FCF total has no matching annual OCF/capex duration; cashConversion: Stored FCF total has no matching annual OCF/capex duration; roce: -32.910672780953576

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fcfMargin: Positive revenue required; zero or negative denominator is unavailable; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -48.26212968801523

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fcfMargin: -11276.523702031602; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -132.27265407280638

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fcfMargin: -3442.7651352511807; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -115.92397620838175

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fcfMargin: -289.71129729441276; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -55.881714526487826

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fcfMargin: Positive revenue required; zero or negative denominator is unavailable; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -77.60132191105671

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fcfMargin: Positive revenue required; zero or negative denominator is unavailable; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -121.42015053958465

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fcfMargin: -838.8631687242798; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -77.08990402550276

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Calculation inputs: {"original":{"fcfTotal":{"value":-19052000,"capex":{"accession":"0001564590-19-006771","end":"2016-12-31","filed":"2019-03-07","form":"10-K","start":"2016-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001564590-19-006771","end":"2016-12-31","filed":"2019-03-07","form":"10-K","start":"2016-01-01","tag":"NetCashProvidedByUsedInOperatingActivities","unit":"USD"}},"revenue":{"value":4628000,"tag":"RevenueFromContractWithCustomerExcludingAssessedTax","unit":"USD","start":"2016-01-01","end":"2016-12-31","filed":"2019-03-07","accession":"0001564590-19-006771","form":"10-K"},"netIncome":{"value":-21698000,"tag":"ProfitLoss","unit":"USD","start":"2016-01-01","end":"2016-12-31","filed":"2019-03-07","accession":"0001564590-19-006771","form":"10-K"},"operatingIncome":{"value":-21906000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2016-01-01","end":"2016-12-31","filed":"2019-03-07","accession":"0001564590-19-006771","form":"10-K"},"openingAssets":{"value":38654000,"tag":"Assets","unit":"USD","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"openingCurrentLiabilities":{"value":2523000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"openingCapitalEmployed":{"value":36131000,"inputNames":["openingAssets","openingCurrentLiabilities"]},"openingParentEquity":{"value":-22207000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2015-12-31","filed":"2019-03-07","accession":"0001564590-19-006771","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":2550000,"tag":"Liabilities","unit":"USD","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"openingCash":{"value":29294000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2015-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2016-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2016-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":-21698000,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2016-01-01","end":"2016-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2016-01-01","end":"2016-12-31","filed":"2019-03-07","accession":"0001564590-19-006771","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":49614500,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: -411.66810717372516; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: -44.15241512057967

Calculation inputs: {"original":{"fcfTotal":{"value":-11190000,"capex":{"accession":"0001564590-18-005404","end":"2015-12-31","filed":"2018-03-13","form":"10-K","start":"2015-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001564590-18-005404","end":"2015-12-31","filed":"2018-03-13","form":"10-K","start":"2015-01-01","tag":"NetCashProvidedByUsedInOperatingActivitiesContinuingOperations","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-11295000,"tag":"NetIncomeLoss","unit":"USD","start":"2015-01-01","end":"2015-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"operatingIncome":{"value":-11315000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2015-01-01","end":"2015-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2014-12-31"},"openingParentEquity":{"value":-11473000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2014-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":2616000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2014-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2014-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":38654000,"tag":"Assets","unit":"USD","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"closingCurrentLiabilities":{"value":2523000,"tag":"LiabilitiesCurrent","unit":"USD","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"closingCapitalEmployed":{"value":36131000,"inputNames":["closingAssets","closingCurrentLiabilities"]},"closingParentEquity":{"value":-22207000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2015-12-31","filed":"2019-03-07","accession":"0001564590-19-006771","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":2550000,"tag":"Liabilities","unit":"USD","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"closingCash":{"value":29294000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2015-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"closingInvestedCapital":{"value":null,"inputNames":["closingBorrowings","closingTotalEquity","closingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2015-12-31"},"closingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingPreferredShares":{"value":0,"tag":"PreferredStockSharesOutstanding","unit":"shares","start":null,"end":"2015-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"closingCommonEquity":{"value":null,"inputNames":["closingParentEquity","closingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"commonNetIncome":{"value":-11523000,"tag":"NetIncomeLossAvailableToCommonStockholdersBasic","unit":"USD","start":"2015-01-01","end":"2015-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"incomeTaxExpense":{"value":0,"tag":"IncomeTaxExpenseBenefit","unit":"USD","start":"2015-01-01","end":"2015-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"pretaxIncome":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"effectiveTaxRate":{"value":null,"inputNames":["incomeTaxExpense","pretaxIncome"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"nopat":{"value":null,"inputNames":["operatingIncome","effectiveTaxRate"],"reason":"Matching annual income-tax expense or supported pretax income unavailable"},"averageInvestedCapital":{"value":null,"inputNames":["openingInvestedCapital","closingInvestedCapital"]},"averageCapitalEmployed":{"value":null,"inputNames":["openingCapitalEmployed","closingCapitalEmployed"]},"averageCommonEquity":{"value":null,"inputNames":["openingCommonEquity","closingCommonEquity"]}},"recovered":{}}; fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2014-12-31

Calculation inputs: {"original":{"fcfTotal":{"value":-7516000,"capex":{"accession":"0001564590-17-005137","end":"2014-12-31","filed":"2017-03-23","form":"10-K","start":"2014-01-01","tag":"PaymentsToAcquirePropertyPlantAndEquipment","unit":"USD"},"ocf":{"accession":"0001564590-17-005137","end":"2014-12-31","filed":"2017-03-23","form":"10-K","start":"2014-01-01","tag":"NetCashProvidedByUsedInOperatingActivitiesContinuingOperations","unit":"USD"}},"revenue":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"netIncome":{"value":-10347000,"tag":"NetIncomeLoss","unit":"USD","start":"2014-01-01","end":"2014-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"operatingIncome":{"value":-8904000,"tag":"OperatingIncomeLoss","unit":"USD","start":"2014-01-01","end":"2014-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"openingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCapitalEmployed":{"value":null,"inputNames":["openingAssets","openingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2013-12-31"},"openingParentEquity":{"value":-1273000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2013-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"openingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCash":{"value":4597000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2013-12-31","filed":"2017-03-23","accession":"0001564590-17-005137","form":"10-K"},"openingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; leases excluded"},"openingInvestedCapital":{"value":null,"inputNames":["openingBorrowings","openingTotalEquity","openingCash"],"reason":"Exact complete borrowings, consolidated equity and cash missing, ambiguous or from different filings at 2013-12-31"},"openingPreferredEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingPreferredShares":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"openingCommonEquity":{"value":null,"inputNames":["openingParentEquity","openingPreferredShares"],"reason":"Common equity scope requires explicit preferred carrying value or zero preferred shares; absence is not zero"},"closingAssets":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCurrentLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCapitalEmployed":{"value":null,"inputNames":["closingAssets","closingCurrentLiabilities"],"reason":"Exact assets/current-liabilities balance missing, conflicting or from different filings at 2014-12-31"},"closingParentEquity":{"value":-11473000,"tag":"StockholdersEquity","unit":"USD","start":null,"end":"2014-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"closingTotalEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingNoncontrollingEquity":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingLiabilities":{"value":null,"reason":"Missing or conflicting matching SEC fact","conflict":false},"closingCash":{"value":2616000,"tag":"CashAndCashEquivalentsAtCarryingValue","unit":"USD","start":null,"end":"2014-12-31","filed":"2018-03-13","accession":"0001564590-18-005404","form":"10-K"},"closingBorrowings":{"value":null,"reason":"No supported complete debt aggregate or non-overlapping borrowing components; 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fcfMargin: No unambiguous matching annual USD fact; cashConversion: Positive net income required; zero or negative denominator is unavailable; roce: matching numerator and positive exact opening/closing CapitalEmployed required; ambiguous scopes remain unavailable; unavailable: openingCapitalEmployed, closingCapitalEmployed; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2013-12-31; Exact assets/current-liabilities balance missing, conflicting or from different filings at 2014-12-31

revenue: 0; operatingIncome: -209562000; netIncome: -155203000

revenue: 0; operatingIncome: -208566000; netIncome: -208018000

revenue: 886000; operatingIncome: -242303000; netIncome: -338790000

revenue: 2329000; operatingIncome: -84781000; netIncome: -83815000

revenue: 18739000; operatingIncome: -65649000; netIncome: -65801000

revenue: 0; operatingIncome: -81481000; netIncome: -80893000

revenue: 0; operatingIncome: -80334000; netIncome: -78254000

revenue: 3888000; operatingIncome: -45463000; netIncome: -44348000

revenue: 5205000; operatingIncome: -27676000; netIncome: -27236000

revenue: 4628000; operatingIncome: -21906000; netIncome: -21698000

revenue: No unambiguous matching annual USD fact; operatingIncome: -11315000; netIncome: -11295000

revenue: No unambiguous matching annual USD fact; operatingIncome: -8904000; netIncome: -10347000